What is Compounded Semaglutide?
Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist — a class of medication that mimics a hormone your body naturally produces after eating. It signals your brain that you're full, slows gastric emptying, and helps regulate blood sugar. The result: significantly reduced appetite, fewer cravings, and more efficient fat loss.
Compounded Semaglutide is administered as a once-weekly subcutaneous injection. Dosing begins low and is gradually titrated upward over several weeks to minimize side effects and allow your body to adjust comfortably.
Clinical trials have demonstrated average weight loss of 15–17% of body weight over 68 weeks with Semaglutide — results that far exceed what most patients achieve through lifestyle modification alone.
What patients typically experience
- Significant reduction in appetite and hunger signals
- Reduced cravings for high-calorie and processed foods
- Steady, sustained fat loss — particularly visceral fat
- Improved blood sugar regulation and insulin sensitivity
- Lower HbA1c in patients with type 2 diabetes or pre-diabetes
- Reduced cardiovascular risk markers
- Improved energy and metabolic function
- Clinically supervised dose titration for comfort and safety
Who is a good candidate?
- Adults with a BMI of 27 or higher with at least one weight-related health condition (high blood pressure, type 2 diabetes, high cholesterol)
- Adults with a BMI of 30 or higher without a related condition
- Those who have struggled to lose weight through diet and exercise alone
- Patients looking for clinician-supervised, evidence-based weight loss support
- Individuals without a personal or family history of medullary thyroid carcinoma or MEN2 syndrome
Common questions
- How is Compounded Semaglutide different from brand-name Ozempic or Wegovy?
- Compounded Semaglutide contains the same active ingredient as Ozempic and Wegovy but is prepared by a licensed compounding pharmacy. It is prescribed and supervised by our clinical team and is often more accessible and cost-effective than brand-name alternatives.
- How quickly will I see results?
- Most patients notice reduced appetite within the first 1–2 weeks. Measurable weight loss typically begins within the first month and continues steadily as dosing is titrated upward. Average clinical trial results show 15–17% total body weight loss over 68 weeks.
- What are the most common side effects?
- The most common side effects are gastrointestinal — nausea, mild bloating, or reduced appetite — particularly during the early dose escalation phase. These typically resolve as your body adjusts. Our clinical team monitors your response and adjusts dosing as needed.
- How do I receive my medication?
- We offer in-office injections administered by our clinical team, or we can train you to self-administer at home. Medication can be picked up at the clinic or shipped directly to your door.
- Is a consultation required before starting?
- Yes. All patients complete a clinical consultation and health history review before beginning any GLP-1 program. This ensures the medication is appropriate for you and that your starting dose and titration schedule are personalized.
Wondering if Tirzepatide might be a better fit?
Tirzepatide activates both GLP-1 and GIP receptors — a dual-action approach that delivers stronger results for many patients. Our clinical team can help you compare both options during your consultation.
HydraSpa Integrative Health
San Antonio, TX
Mon – Fri: 9am – 5pm | Sat: By appointment
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